He Yuan, Mou Qiang, He Yubing, Zhao Xiaoyan, Wang Jian, Zhou Guomin, Zhang Jianhua ...
Gastrointestinal tract bacteria require iron for survival, with heme as an abundant source in their environment. This work ...
“While the rest of the genome shuffles between the maternal and paternal origins, centromeres are inherited intact: one from ...
This fundamental study presents a compelling and comprehensive analysis of the newly defined Lipocone superfamily, offering unprecedented insights into the evolutionary origins of Wnt proteins. The ...
Abstract: Genome sequence analysis is fundamental to medical breakthroughs such as developing vaccines, enabling genome editing, and facilitating personalized medicine. The exponentially expanding ...
This study provides an important computational tool for analyzing and deconvoluting a pool of plasmids sequenced without barcoding using nanopore long-read sequencing. The tool, which has been ...
A bioRxiv preprint is also currently underway. SEAM provides a unified interface for mechanistic interpretation of sequence-based deep learning models. The framework takes as input a sequence-based ...
Sequence variant analysis (SVA) is critical in therapeutic protein development as it ensures the absence of genetic mutations during cell culture. Sequence variant analysis aims to identify and ...
The formation of biomolecular condensates through the process of phase separation is thought to be a central organizing principle underlying cellular matter and has been shown to play a key role in ...