Cats should be at least 8 weeks old to receive selamectin/sarolaner topical. Give selamectin/sarolaner topical every 30 days (monthly) without stopping for best results.

It does contain Sarolaner which is a member of the isoxazoline class. This class of drugs is associated with adverse neurological reactions such as ... Let’s also address flea prevention in cats.

~$303.80 = Cost of 12 doses of Simparica Trio™ (sarolaner, moxidectin, and pyrantel chewable tablets). Retail pricing based on two 6 PKs (72MG) at $151.90 per 6 PK.

Complementary studies have also evaluated combination therapies; for instance, a 2020 investigation into a topical sarolaner-selamectin formulation on naturally infested cats confirmed rapid and ...