A Northwestern Medicine study has uncovered distinct roles for major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics, according to findings published in the ...
Proteomics is the study and analysis of proteins, including their structures, functions, interactions, and modifications within a biological system. Humans have approximately 20,000 genes that produce ...
New research led by the University of Exeter has shed light on the complexity of gene expression in the brain by characterizing the extent of isoform diversity in the human and mouse cortex, including ...
Gene isoforms are different variations or versions of a gene that can be produced by alternative splicing or alternative transcription initiation and termination. These isoforms are often present in ...
What happens if a protein-based biotherapeutic includes unexpected isoforms? Traditional, analysis might not even reveal very similar isoforms in a biotherapeutic. So, Jonathan Bones, PhD, principal ...
The NRAS gene, known to play a fundamental role in cancer development, produces five gene variants, or isoforms, rather than just one form, as thought, new research shows. The study identified four ...
Joshua C. Snyder is in the Departments of Surgery and Cell Biology, Duke University School of Medicine, Durham, North Carolina 27710, USA. Marti-Solano and colleagues set out to determine how the ...
4-D separation system is expected to allow accurate mapping of proteomics data to phenotype. Scientists say a new ‘top-down’ approach to identifying individual proteins at the proteome-wide scale can ...
New research led by the University of Exeter has shed light on the complexity of gene expression in the brain by characterizing the extent of isoform diversity in the human and mouse cortex, including ...