DEA designates bromazolam as Schedule I, boosting enforcement and awareness of its deadly risks after push from 22-state coalition.

San Diego County sheriff’s homicide detectives are investigating the shooting death of a man in Jamul on Wednesday.

As gas prices skyrocket, the San Diego Metropolitan Transit System Wednesday released a commute cost calculator to show motorists how much money they could save by riding public transit.

For many Padres fans, spring training in Peoria, Arizona, is a chance to catch a game or get a glimpse of a favorite player. But for one couple, it has become a much bigger part of their lives.

An AI-powered car-buying service called CarEdge is gaining national attention for helping consumers get better deals — ...

The United Farm Workers union says it won't participate in any celebrations of founder Cesar Chavez amid what it is calling troubling but unspecified allegations.

Prepare yourself for another unusually hot day for March. Heat advisory now extending from the coast to the mountains, and ...

On March 14, deputies were dispatched to a home in the 6300 block of El Apajo after a resident “advised that a house party was out of control and they needed assistance with removing attendees.” ...

Top national security officials testified Wednesday before the Senate Intelligence Committee on worldwide threats.

Major U.S. airlines say strong ticket sales are offsetting soaring jet fuel costs linked to the war in the Middle East.

A man walking to a Mountain View convenience store Tuesday evening was stabbed by an unknown assailant, according to San Diego police.

Amid a rise in hate crimes, the San Diego City Council adopted a definition of antisemitism from the International Holocaust ...