Phosphoproteomic profiling of Osimertinib drug-tolerant persister (DTP) cells identified dynamic signaling transitions and ...

Hypoxia, or low oxygen in the body, is common in solid tumors. Now, researchers have identified that an RNA molecule, EUDAL, ...

An expert discusses the MARIPOSA study’s impact on managing central nervous system (CNS) involvement in EGFR-mutated non–small cell lung cancer, emphasizing improved brain progression-free survival, ...

Treating constipation with lubiprostone may confer renal benefits in chronic kidney disease by modulating microbiome-driven ...

Oral cancer is one of the most common head and neck cancers worldwide, with hundreds of thousands of new cases diagnosed every year. Despite advances in surgery, radiotherapy, and chemotherapy, ...

EGFR is tagged by c-Cbl/Grb2 for breakdown inside lysosomes. In hypoxia (right), the RNA molecule EUDAL prevents this process, keeping EGFR permanently active. This activates the STAT3/BNIP3 pathway, ...

At 12 months, mean eGFR was 51.5 mL/min/1.73m2 in the imlifidase arm versus 19.3 mL/min/1.73m2 in the control arm with a statistically significant and clinically meaningful difference of 32.2 mL/min/1 ...

Researchers have determined in a new study that albuminuria, and not diminished kidney function, is independently associated ...

Jacobiopharma (1167.HK) announced today that the company's Chairman and CEO, Dr. Wang Yinxiang, along with concerted parties, has recently accumulated a total of 11,058,700 shares of the company, ...

Jacobio Pharmaceuticals (1167.HK) today announced that its Chairman and Chief Executive Officer, Dr. Yinxiang Wang, together with concerted parties, have recently increased their shareholding in the ...