Clemson is all but certain to make it 21 straight years in a bowl game after an upset win over Louisville. Here's who and ...

Louisville lost this game because of missed opportunities. However, no game comes down to a handful of mistakes or misses. It ...

The Clemson Tigers upset the Louisville Cardinals in a Week 12 ACC college football game on the road. Here are the highlights ...

The Clemson Tigers earned a 20-19 victory over the Louisville Cardinals in Week 12 of the college football season. Here are ...

Kickoff from L&N Federal Credit Union Stadium in Louisville, Ky., is at 7:30 p.m. ET. The Cardinals are 1.5-point favorites ...

Here's a look at how social media reacted to Clemson heading to Louisville and picking up a much-needed ranked win.

Clemson looks to make a bowl game and spoil Louisville's CFP hopes with a win in Week 12. Here's what to know about the game ...

Clemson took a decent climb up the rankings in USA TODAY Sports' latest 1-136 re-rank after Clemson took down Louisville.

With the lead and great field position, Clemson looked ready to close things out, but a dropped pass and a bad punt snap ...

Dabo Swinney and the Clemson Tigers look to avoid a second straight loss to Jeff Brohm and Louisville. Here's ESPN SP+'s score prediction for Friday.

Our Clemson vs Louisville predictions, odds and college football picks for Friday, November 14 expect Cade Klubnik & Co. to ...

Louisville football fans were heartbroken after their team's brutal collapse that led to a 20-19 loss to ACC rivals Clemson.