Protein, but not mRNA, levels of neurodegenerative disease-associated protein TDP-43 are decreased upon knockdown of BORC, a complex that is required for the anterograde transport of lysosomes.
This review focuses on the vital interconnections among lysosomes, iron metabolism, and mitochondria in osteoclasts.
Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen ...
News-Medical.Net on MSN
Lysosomal acidity fine-tunes reactive species production in macrophages
Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen ...
Discover how a high-fat diet affects memory formation and cognitive health. Learn about the research findings on the impact ...
HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing ...
Research in C. elegans shows that longevity-related changes in lysosomes can be passed from parents to offspring ...
Traditional studies in cell dynamics rely on manual labeling and trajectory analysis, making it challenging to cope with the high throughput of data and the complexity of lysosomal movement under ...
News-Medical.Net on MSN
Lysosomal activity in worms linked to transgenerational extension of lifespan
In the Wang Lab, it's not unusual for worms to live for a long time. HHMI Janelia Research Campus Senior Group Leader Meng ...
Modern lifestyles and dietary changes have significantly increased the consumption of high-fat foods, contributing to a steep ...
Techno-Science.net on MSN
🧠Eating too much fat affects your long-term memory
Our diet directly influences the clarity of our mind. A recent study sheds light on the cellular mechanisms by which high-fat ...
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