A combination of cryogenic electron microscopy and molecular simulations has been used to study the structure and dynamics of an enzyme called ACE.

Switching off a single enzyme in immune cells protected mice from obesity, type 2 diabetes, and fatty liver disease in a new ...

Structural and computational approaches uncover the molecular basis for dimerization, open-closed conformational transitions, and the dynamic behavior of the human angiotensin-I converting enzyme ...

Cannabidiol (CBD) shows promise in regulating appetite, glucose and lipid metabolism, and inflammation in preclinical models ...

Profs Ravi Acharya and Edward Sturrock review the historical foundation, present landscape and future clinical promise of ACE inhibition.

Neurodegenerative diseases such as Alzheimer’s disease and related disorders, are characterized by progressive decline in cognitive function and neuronal ...

Researchers from Queen Mary University of London's School of Biological and Behavioral Sciences, using the simple fission ...

Study in fission yeast revealed a key role for a set of enzymes called agmatinases, which break down the metabolite agmatine into polyamines.

Steviol glycosides, natural sweeteners extracted from Stevia rebaudiana, are widely used as sucrose substitutes due to their ...

A new study led by Stephen Withers from the University of British Columbia introduces a technique for engineering much more ...

IGF2BP3 links cancer metabolism and RNA control, offering a potential new therapeutic target for blocking leukemia cell growth.

An international team led by Monash University and Baylor College of Medicine, Texas, has found "switching off" an enzyme called CaMKK2 in immune cells that drive inflammation prevents diet-induced ...