Researchers are calling for an urgent overhaul of diagnostic and treatment guidelines for infections in newborn babies, after ...
The way antibiotics called polymyxins pierce the armour of bacteria has been revealed in stunning detail by high-resolution ...
The new study, published in the journal Nature Microbiology, revealed in high-resolution images and biochemical experiments ...
A team led by UCL (University College London) and Imperial College London researchers has shown for the first time how ...
The University College London and Imperial College London focused on antibiotics called Polymyxin B, which kill harmful Gram-negative bacteria like E. coli. These bacteria are highly difficult to ...
Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis, while sparing healthy microbes in the mouse ...
Researchers have revealed how polymyxins, crucial last-resort antibiotics, break down bacterial armor by forcing cells to ...
LpxC inhibitors target a zinc-dependent deacetylase that catalyses the first committed step in lipid A biosynthesis, an essential process for the viability of Gram-negative bacteria. As lipid A forms ...
In a recent study published in the journal Nature, researchers in the United States of America designed and discovered lolamicin, a selective antibiotic that targets the lipoprotein transport system ...
Total non-dilutive funding of up to USD 159 million upon completion of predefined milestones, including near-term committed ...