In this important work, the authors present a new transformer-based neural network designed to isolate and quantify higher-order epistasis in protein sequences. They provide solid evidence that higher ...
This study provides an important computational tool for analyzing and deconvoluting a pool of plasmids sequenced without barcoding using nanopore long-read sequencing. The tool, which has been ...
A bioRxiv preprint is also currently underway. SEAM provides a unified interface for mechanistic interpretation of sequence-based deep learning models. The framework takes as input a sequence-based ...
Sequence variant analysis (SVA) is critical in therapeutic protein development as it ensures the absence of genetic mutations during cell culture. Sequence variant analysis aims to identify and ...
ABSTRACT: This study evaluated the molecular characterization of different ecotypes of B. aegyptiaca populations in the four sites: Koily alpha, Labgar, Ranérou and Ballou according to the environment ...
Hello developers, thank you for creating the Dorado tool. I have received a lot of help from it. Recently I've been dealing with my nanopore DRS data, and at this stage we'd like to explore some polyA ...
Infectious diseases caused by pathogenic microorganisms pose a serious threat to human health. Despite advances in molecular biology, genetics, computation, and medicinal chemistry, infectious ...
Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, School of Animal Science and Technology, Foshan University, Foshan, China Introduction: Porcine reproductive and ...
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