WE have recently reported 1 that the oxidation of pyruvate by finely ground preparations of pigeon's brain is catalysed by fumarate and adenylic acid (or adenosine triphosphate). The effect of ...
The FDA has issued a CRL to Saol Therapeutics regarding the NDA for SL1009 (sodium dichloroacetate oral solution) for the treatment of pyruvate dehydrogenase complex deficiency.