First, the BAC clone DNA is denatured into single stranded templates. Each of the three DOP-PCR primers used in the next step is flanked by known 5' and 3' anchor sequences with six random nucleotides ...

Understanding chromosome organization is crucial for plant genetics, but many tropical fruit crops lack reliable tools for ...

Therapeutic oligonucleotides act on different stages of pathological gene expression. Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription ...

Although the concept of using synthetic oligonucleotides to modulate RNA function was described as early as 1978, 1 its realization in the form of drugs approved by the Food and Drug Administration ...

Today, PCR is ubiquitous in molecular biology laboratories. As one of the first experiments that young scientists master, it is easy to take for granted. But developing this research lab staple ...

Eurogentec obtained a license from Applied Biosystems to manufacture and sell dual-labeled oligonucleotide probes worldwide for use in the 5´ Nuclease process. This process is one of the key ...

WuXi AppTec’s STA Pharmaceutical contract manufacturing business and Regulus Therapeutics have launched an oligonucleotide synthesis and manufacturing collaboration. STA will work with the biotech ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 10 (May 14, 2002), pp. 6597-6602 (6 pages) The creation of novel enzymatic function is of great interest, ...

A set of 18 accessions from an Indian scented rice (Oryza sativa L.) collected was subjected to random amplified polymorphic DNA (RAPD) analysis. Polymerase chain reaction (PCR) with 10 arbitrary ...

TriLink and Maravai say their new $50 million San Diego facility, within TEN770 (10770 Wateridge Circle), has room for additional growth. A San Diego manufacturer of highly-modified nucleic acids and ...