The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea.

Simparica products are chewable tablets that prevent, control, and treat fleas, ticks, and heartworms in dogs.

A Windham dog owner blames Simparica Trio for the death of his dog. Ted DeSalvo says his veterinarian didn’t warn him about the possible side effects.

The study included dogs that were randomly allocated to one of four treatment groups: Credelio, Simparica TRIO, NexGard or untreated control. Live tick counts were performed on dogs by blinded ...

Owners that have dogs with a history of seizures or neurologic disorders are told to use Simparica Trio with caution. DeSalvo questioned: 'Why are those warnings on the box if it’s safe?' ...

Ted DeSalvo’s dog, 3-year-old Greta, was euthanized last month. He blames her death on Simparica Trio, a chewable tablet used to protect dogs against heartworm disease, ticks and fleas.

Owners that have dogs with a history of seizures or neurologic disorders are told to use Simparica Trio with caution. DeSalvo questioned: 'Why are those warnings on the box if it’s safe?' ...

The company said: “We are confident that Simparica Trio, which has been prescribed to protect over 10 million dogs since coming to the U.S. market in 2020, remains an effective and safe parasite ...

The company said: “We are confident that Simparica Trio, which has been prescribed to protect over 10 million dogs since coming to the U.S. market in 2020, remains an effective and safe parasite ...