UCB's ongoing commitment to advancing research for people living with epilepsiesData include an open-label extension study describing the long-term safety of FINTEPLA®▼ (fenfluramine)[1] and global ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. The study by Druker et ...

The magnesia (MgO) hydroxylation behavior in dilute suspensions (below 50% volumetric solid loads) has been extensively studied over the past decades due to its role in refractory castables. However, ...

Acute myocardial infarction (MI) remains one of the major causes of death worldwide, and innovative treatment strategies for MI represent a major challenge in cardiovascular medicine. Caloric ...

Matthew E. Cockman, Yoichiro Sugimoto, Hamish B. Pegg, Norma Masson, Eidarus Salah, Anthony Tumber, Helen R. Flynn, Joanna M. Kirkpatrick, Christopher J. Schofield, Peter J. Ratcliffe Proceedings of ...

Aryl hydrocarbon hydroxylase, an inducible microsomal enzyme system, has been measured in cultures of normal and transformed hamster, mouse, and human cells. In order to determine the highest level of ...

Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Laboratory of Photochemistry, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese ...

Aziridine is a key functional group that is presented in natural products. Due to its inherent ring strain, aziridine displays remarkable reactivity in targeting and disrupting the DNA bases of cancer ...

For diverse human tumors, growth and metastasis are dependent on proline synthesis, but the mechanisms underlying this association are not clear. Proline incorporated into collagen is primarily ...

An environmentally benign method is described for the α-hydroxylation of malonates and cyclic analogues in aqueous medium at room temperature under mild conditions, based on the in situ generation of ...