This manuscript reports valuable results on the role of MDC1 and Treacle in DSB repair in rDNA repeats. It has been previously established that MDC1 is replaced by Treacle as the main adaptor in the ...
Gene editing in plants remains challenging, with the traditional non-homologous end-joining (cNHEJ) repair pathway often ...
BioLineRx Ltd. (NASDAQ: BLRX) (TASE: BLRX), a clinical development stage biopharmaceutical company pursuing life-changing therapies in oncology and rare diseases, and Hemispherian AS, a Norwegian ...
Jasin's fundamental research on repair of damaged DNA in cells has transformed our understanding of cancers linked to ...
When a key protein regulator dials down DNA repair mechanisms, our cells accumulate more mutations, which may cause us to age ...
A new study in fruit flies describes how an animal's gut reacts differently to beneficial microbes versus harmful pathogens.
A research team led by scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) has introduced a new ...
Reporting in Nature, scientists have identified a novel process that protects the ends of chromosomes from incorrectly applied DNA repair. Although DNA repair is a crucial mechanism that can protect a ...
Human fertility hinges on a delicate molecular ballet that begins even before birth. UC Davis researchers have uncovered how special protein networks safeguard chromosomes as eggs and sperm form, ...
Junk DNA” may hold the key to treating tough cancers. Existing drugs exploit weaknesses in cells with gene mutations. Researchers at King’s College London have identified a promising strategy for ...