We used immunohistochemistry to assess 124 NEC tumor samples from any primary site for DLL3 and 53 for SEZ6 and defined positivity as ≥1% staining. We describe the landscape of DLL3 and SEZ6 ...
It is no longer science fiction: human embryos have now been made from DNA in skin cells that were fertilised with sperm, a ...
Polyploid crops often display enhanced vigor, larger organs, and unique reproductive behaviors, making polyploidization a ...
Structurally-guided discovery using high-resolution cryo-EM has delivered potent, DCAF16-dependent Targeted Glues™ of SMARCA2, with exquisite selectivity over close homolog, SMARCA4.Rapid, deep and ...
Chitons are marine mollusks that can scrape off and feed on algae from rocky surfaces using their ultrahard magnetic teeth.
Amphista Therapeutics discloses first details of its TEAD Targeted Glue™ program and unveils new mechanism of action for TEAD degradation via ...
In a study published in Science, researchers found that the defense protein "Resistin like molecule gamma" (Relmy), produced by neutrophils, punches holes into heart cells after a heart attack. This ...
Novel Vitamin K equivalents may penetrate the brain and induce neuron growth, offering promise to treat Alzheimer’s, Parkinson’s, and other brain disorders.