Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Teneurins are conserved cell adhesion ...
The Tācell receptor (TCR)āCD3 complex is critical for Tācell development and function, and represents one of the most complex transmembrane receptors. Models of different stoichiometry and valency ...
The ups and downs of caloric restriction and fasting: from molecular effects to clinical application
Ageāassociated diseases are rising to pandemic proportions, exposing the need for efficient and lowācost methods to tackle these maladies at symptomatic, behavioral, metabolic, and physiological ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. CD8 + T cells have critical roles in tumor ...
TRAF6āmediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor
Figure 3. NRIF is polyubiquitinated by the E3 ubiquitin ligase TRAF6. HEK 293 cells were cotransfected with FlagāNRIF, FlagāTRAF6 or HAāubiquitin, then lysed in SDS lysis buffer and the lysates were ...
Department of Microbiology and Division of Developmental and Clinical Immunology, University of Alabama at Birmingham, Birmingham, AL, 35294-3300 USA ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Tābox family transcription factors have ...
An 11.7āÅāresolution cryoāEM map of the yeast 80S·eEF2 complex in the presence of the antibiotic sordarin was interpreted in molecular terms, revealing large conformational changes within eEF2 and the ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Auxin dictates root architecture via the Auxin ...
The human body strives to control the concentration of blood glucose within a narrow range, by using counterbalancing hormones. When we ingest sugar, the surge in blood glucose triggers the release of ...
Faculty of mathematics and computer science, Weizmann Institute of science, Rehovot, Israel Department of molecular genetics, Weizmann Institute of science, Rehovot, Israel The Blavatnik School of ...
Nonsenseāmediated mRNA decay (NMD) is an mRNA surveillance pathway that recognizes and degrades aberrant mRNAs containing premature stop codons. A critical protein in NMD is Upf1p, which belongs to ...
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