Scientists have identified a promising target for treatment of a devastating autoimmune disease affecting the brain.
When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...
20hon MSN
OHSU researchers identify key trigger behind brain disorder often mistaken for mental illness
A new OHSU study shows how the immune system can quietly disrupt brain function — and why the disease is often hard to ...
Hosted on MSN
First-ever image of an open NMDA receptor reveals clues to how neurodegenerative disease occurs
When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...
Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...
The images showed that nearly all the antibodies bind to a single domain of the receptor, providing a viable target for novel therapeutics.
Three distinct snapshots obtained with cryo-electron microscopy illustrate the arrangement of two of the four symmetrical subunits that make a functional NMDA receptor. During activation, as the ...
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