CD4+ T cells, or helper T cells, are one type of lymphocyte that helps coordinate the immune response against infection and disease. They interact and activate other cells in the immune system. The ...

Researchers found that CD4+ T cells can be classified into 18 categories and 12 distinct gene programs, and that characteristic changes in CD4+ T cell profiles are associated with autoimmune disease, ...

In a recent article published in the Cell Reports Journal, researchers used a preclinical mouse model to demonstrate that T helper 1 (Th1) effector memory cluster of differentiation 4 (CD4) + T cells ...

Researchers have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity. The pre-clinical findings highlight the potential to ...

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with ...

Certain levels of urinary CD4+ T lymphocytes in patients with ANCA-associated vasculitis have a 60% and 98% sensitivity and specificity, respectively, for predicting future renal flares. Urinary CD4+ ...

In a recent study published in EBioMedicine, a group of researchers determined the impact of nicotinamide mononucleotide (NMN) on Clusters of differentiation 4 + (CD4 +) Thymus cells (T cells) viz. T ...

Abnormal expansion of PD-1+ T lymphocytes may be a sign of lupus nephritis onset in patients with SLE. Elevated PD-1+CD4+ T cells represent an independent risk factor for lupus nephritis (LN) and may ...