The way antibiotics called polymyxins pierce the armour of bacteria has been revealed in stunning detail by high-resolution ...
Researchers are calling for an urgent overhaul of diagnostic and treatment guidelines for infections in newborn babies, after ...
Gram-negative meningitis is a form of meningitis. The term gram-negative refers to a way of differentiating bacteria. This type of bacteria is typically resistant to drugs and most available ...
The new study, published in the journal Nature Microbiology, revealed in high-resolution images and biochemical experiments ...
Researchers have revealed how polymyxins, crucial last-resort antibiotics, break down bacterial armor by forcing cells to ...
Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis, while sparing healthy microbes in the mouse ...
Clostridium perfringens is a spore-forming bacteria that can function without oxygen (anaerobic bacteria). These gram-positive bacteria are typically found in human and animal intestines. Bacteria are ...
In a recent study published in the journal Nature, researchers in the United States of America designed and discovered lolamicin, a selective antibiotic that targets the lipoprotein transport system ...
LpxC inhibitors target a zinc-dependent deacetylase that catalyses the first committed step in lipid A biosynthesis, an essential process for the viability of Gram-negative bacteria. As lipid A forms ...
The University College London and Imperial College London focused on antibiotics called Polymyxin B, which kill harmful Gram-negative bacteria like E. coli. These bacteria are highly difficult to ...
Endotoxin, a toxic chemical found in bacteria, makes up only 0.0001% of PM2.5 fine particles but packs a serious punch when ...