There is a high unmet need for accessible, affordable, and high-quality fertility care, as approximately 1 in 6 people are affected by infertility worldwide. While meiotic failure is a major cause of ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimislecel ...