The focus of most current PAH treatments is vasodilation, with 3 main targets including the endothelin (ET), prostacyclin (PGI2), and nitric oxide (NO) signaling pathways to relax constriction in ...

Please provide your email address to receive an email when new articles are posted on . Risks for rebleeding and mortality were similar regardless of vasoconstrictor therapy duration. Data support ...

Efforts thus far to interrupt the neurological dysfunction underlying Raynaud's have come up short and there aren't many others in the offing, said Frederick M. Wigley, MD, of Johns Hopkins University ...

Impaired vascular function leads to cardiovascular disease. Researchers have found that prolonged sitting impairs forearm cutaneous vasodilation function. They also showed that alternating local skin ...

EXPERIMENTS were performed on aglomerular fish kidneys to establish the presence or absence of vaso-active substances. This communication deals with the presence of an adrenolytic, vasodilator ...

Inhaled nitric oxide (NO) is a selective pulmonary vasodilator that significantly reduces the neonatal morbidity and mortality associated with pulmonary hypertension (1,2). Given the cost and need for ...