Nitrogen is a big part of the air we breathe, but too much can kill. Researchers at Johns Hopkins University reviewed 25 years of studies on using sodium phenylacetate and sodium benzoate to help ...

DUBLIN--(BUSINESS WIRE)--Horizon Therapeutics plc (Nasdaq: HZNP) in partnership with Invitae Corporation (NYSE: NVTA) today announced a new urea cycle disorder (UCD) genetic testing program designed ...

Inborn errors of urea synthesis lead to an accumulation of ammonia in blood and brain and result in high rates of mortality and neurodevelopmental disability. This study seeks to characterize the ...

An international research consortium co-led by Andrea L. Gropman, M.D., at Children's National Hospital has received $5 million in federal funding as part of an overall effort to better understand ...

The application was approved through the FDA’s 505(b)(2) regulatory pathway. The Food and Drug Administration (FDA) has approved Olpruva ™ (sodium phenylbutyrate) as an oral suspension for the ...

Anticipate submitting New Drug Application in early 2021 assuming successful completion of additional non clinical work and 12-month long-term stability data NEWTON, Mass., Feb. 24, 2020 (GLOBE ...

(MENAFN- EIN Presswire) EINPresswire/ -- What Is The Expected Cagr For The Urea Cycle Disorders Treatment Market Through 2025? In recent times, the market size for treatment of urea cycle disorders ...

The National Urea Cycle Disorders Foundation (NUCDF), the leading patient advocacy group for people affected by urea cycle disorders (UCDs), today announced the launch of a two-year national project ...

A 25-year study at 118 U.S. hospitals has demonstrated the effectiveness of a simple treatment for a mind-destroying, frequently lethal family of genetic diseases called urea cycle disorders. The ...

Arginase deficiency is a rare autosomal recessive metabolic disorder that disrupts the final step of the urea cycle, impairing the conversion of arginine into urea and ornithine. In affected ...

ACER-001, a nitrogen-binding agent, is a powder formulation of sodium phenylbutyrate designed using a microencapsulation process. The Food and Drug Administration (FDA) has accepted for filing the New ...