Phosphatidate phosphatase (PAP) enzymes play a pivotal role in lipid metabolism, acting as a control point that directs metabolic flux between membrane phospholipid synthesis and the production of ...
Method：Method to Decrease Triglyceride Synthesis in the liver; Formulations: MN-001 (Tipelukast) can be administered in various forms; Administration: The compound can be administered orally, in ...
Kim S, Chung J, Arlt H, Pak AJ, Farese RV Jr, Walther TC, Voth G. (2022) Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane. Elife ...
Triglyceride (TG) levels are a measure of cardiovascular (CV) risk and a target for therapy, but a focus on TG levels as a bad guy in CV risk assessments may be missing the mark, a population-based ...
Pharmaceutical Technology on MSN
Ionis and Sobi’s Tryngolza gains approval in EU for FCS treatment
Ionis and Sobi have announced European Union (EU) approval for Tryngolza for adults with familial chylomicronemia syndrome ...
The allowed claims cover a groundbreaking method for decreasing triglyceride synthesis in the liver by administering MN-001 (Tipelukast) or its metabolite or pharmaceutically acceptable salt. This ...
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