Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

The process of 'translation' in protein synthesis involves formation of a peptide bond between two amino acids that are attached to two distinct transfer RNAs (tRNAs). For long, scientists have been ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

To better understand how RNA in bacteria gives rise to protein -- and potentially target these processes in the design of new antibiotics -- researchers are turning their attention to the unique way ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Researchers showed that many mitochondrial proteins enter the organelle during synthesis, guided by folding patterns and structural signals. This discovery revises decades of biochemical models. Mitoc ...

With the principles of molecular biology very much in the zeitgeist these days, we thought it would be handy to provide some sort of visual aid to help our readers understand the complex molecular ...

Reining in protein production could have therapeutic effects on bladder tumors, according to new work published today in the journal JCI Insight. “This is the first time that it’s been shown that ...

Two projects at the University of California, Davis, that use artificial intelligence to design and engineer proteins for ...

The genetic information stored in DNA is “decoded” to form proteins via the process of translation. This involves the formation of peptide bonds between amino acids bound to transfer RNA (tRNA) ...