The deubiquitinase USP17LA negatively regulates T-cell activation and attenuates anti-tumor immunity
USP17LA loss enhances T-cell function and anti-tumor activity in murine tumor models. Usp17la-deficient T cells exhibit ...
T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...
Beta version of PredicTcell™ expands training dataset to ~1.4 million and total dataset to over 6.7 billion records. Potential future T cell ...
UCSF researchers designed a CAR T-cell therapy and combined it with an older class of diabetes drugs called ...
The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...
SciTech Development, Inc., a clinical-stage oncology company advancing its innovative nanotechnology-enabled cancer drug, ...
X™ T-Cell Transduction Sponge is honored in the Lab Research Tools category of the 2025 Top Innovations contest.
Researchers have harnessed the power of artificial intelligence to tackle one of the most complex challenges in immunology: predicting how T cells recognize and respond to specific peptide antigens.
SciTech Development Inc., a clinical-stage oncology company in Detroit, has closed its Convertible Note Round No. 3 (CNR 3) ...
A genetic mutation commonly found in cancer patients may also affect how the human body develops in the womb, according to ...
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