T lymphocytes are central components of the adaptive immune system, tasked with recognising and responding to a wide array of antigens. Their activation is initiated through the engagement of the T ...

Mayo Clinic researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell therapy, or CAR-T cell therapy. Over time, the engineered immune ...

Cancer immunotherapy has revolutionized treatment for many patients, but significant challenges remain in predicting who will respond to these life-saving treatments. A new comprehensive review ...

In a recent study published in Nature Immunology, researchers investigated whether stem-like T lymphocytes are involved in ulcerative colitis (UC) pathogenesis. UC is an inflammatory illness ...

Association of tumor-infiltrating lymphocytes (TILs) and immune signatures with PAM50 intrinsic subtyping hormone receptor-positive (HR+)/HER2-negative (HER2-) early breast cancer (BC): A ...

In a recent study published in Nature Immunology, researchers investigated the direct influence of sodium (Na+) ions on the cytotoxic cluster of differentiation 8 (CD8)-expressing T cells and hence on ...