A cell has many ways to regulate gene expression, one of which is the structure of the genome itself; active genes have to be accessible to the cellular machinery to be expressed. The DNA in the ...

Tiny robots could serve all kinds of useful functions, but shrinking their actuators has proven challenging. Now researchers at the University of Wollongong (UOW) in Australia have made artificial ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...

DNA, the diverse combination of just four nucleotide letters that writes our genetic code, can do more than just form a double helix. In a new study from the National Institutes of Health (NIH) and ...

As it squeezes down the chromatin fiber, the cohesin protein complex extrudes a growing loop of DNA -- a bit like the quick-lacing system of trail-running shoes. But what is powering the movement of ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, No. 16 (Aug. 15, 1989), pp. 6121-6125 (5 pages) Incubation of topologically relaxed plasmid DNA with simian ...

The double helix of DNA is one of the most iconic symbols in science. By imitating the structure of this complex genetic molecule we have found a way to make artificial muscle fibers far more powerful ...

A team of physicists working at the intersection of theory and experiment are shedding new light on the “teamwork” of molecular motors—called RNA polymerases (RNAPs)—that mediate DNA transcription.

As it squeezes down the chromatin fibre, the cohesin protein complex extrudes a growing loop of DNA - a bit like the quick-lacing system of trail-running shoes. But what is powering the movement of ...

A team of physicists working at the intersection of theory and experiment are shedding new light on the 'teamwork' of molecular motors -- called RNA polymerases (RNAPs) -- that mediate DNA ...