Alveolar fibroblasts play a key role in regulation of lung inflammation. Pseudomonas aeruginosa (PAO) is one of the most ...

Patricia F. Lalor, Ph.D.; 1 Jeff Faint, Ph.D.; 1 York Aarbodem, M.Sc.; 1 Stefan G. Hubscher, F.R.C.Path.; 1 David H. Adams, M.D., F.Med.Sci.1 ...

Under normal conditions, cytokines aid in pathogen recognition and elimination while contributing to immune system homeostasis. When the immune system malfunctions, irregularities in cytokine ...

Ovarian cancer treatment faces challenges with high relapse and drug resistance rates, despite initial chemotherapy effectiveness. Cytokines like IL-6 and IL-11 are associated with complex tumor ...

Cytokines are secreted proteins critical for immune regulation, cell signaling, and tissue homeostasis. These cells are increasingly recognized as key tools in biomedical research, particularly in ...

Induced pluripotent stem cells (iPSCs) are a flexible source of tissue models for drug discovery, cancer research and disease modeling; however, differentiation of iPSCs into somatic tissues requires ...

Molecular biologists and biochemists these days are focusing an increasing share of their investigations on the activities of a class of small peptide messenger molecules called cytokines. The ...

Schematic of the early-stage characteristics of house dust mites-induced bronchial fibroblasts, which are characterized by suppressed extracellular matrix production alongside activated inflammatory ...

Cytokines are a large group of bioactive small molecule proteins synthesized and secreted by immune and non-immune cells. There are various types of cytokines that belong to different families and ...