Recombinant DNA technologies developed in the early 1970s enabled scientists to isolate genes of interest and splice them into existing DNA structures. However, as late as the early 1980s, the ...

One of the greatest transformations in modern medicine arguably began with a corned beef sandwich. It was the late 1960s, and new Department of Medicine Chair Lloyd Hollingsworth “Holly” Smith Jr., MD ...

A deficiency of AS (citrullinemia), the third enzyme in the urea cycle is inherited as an autosomal recessive trait.1 The prevalence has been estimated as approximately one in 100 000.2 A complete ...

The first peer-reviewed journal in the field of human gene therapy, providing all-inclusive coverage of the research, methods, and clinical developments that are driving today's explosion of gene ...

In a recent study posted to the bioRxiv* preprint server, researchers developed a human endogenous retrovirus (HERV)-enveloped recombinant baculoviral deoxyribonucleic acid (DNA) vaccine to target the ...