WE have recently reported 1 that the oxidation of pyruvate by finely ground preparations of pigeon's brain is catalysed by fumarate and adenylic acid (or adenosine triphosphate). The effect of ...
Mitotic kinase CDK1 phosphorylates LDHA at T18, reducing its incorporation into LDH tetramers and promoting formation of LDHB-enriched tetramers during mitosis. This accelerates lactate-to-NADH ...
The FDA has issued a CRL to Saol Therapeutics regarding the NDA for SL1009 (sodium dichloroacetate oral solution) for the treatment of pyruvate dehydrogenase complex deficiency.
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