Base editing is a precision genome-editing methodology that enables the programmable installation of point mutations with high efficiency. Two major classes of base editors have been developed: ...

Base editors enable the direct conversion of target nucleotides without introducing DNA double strand breaks, making them a powerful tool for creating point mutations in a human genome. However, ...

The trajectory of base editing has been remarkable, progressing from the laboratory to patient care, treating debilitating or terminal illnesses, in less than a decade. A type of gene editing that ...