A new study in The Journal of Immunology reveals how a high-fat diet may impair the immune system's ability to respond to infection by impacting the function of neutrophils, one of the first immune ...

Figure 1: Mechanisms involved in regulation of tumor progression by neutrophil PAD4. “Using several transplantable and genetically engineered mouse models, we demonstrated that tumor growth was ...

Hospitalized older adults with community-acquired pneumonia (CAP) and sepsis exhibit impaired neutrophil function; however, glycolytic metabolism is not the driver of neutrophil dysfunction. This ...

Heart attacks that occur at night are less severe than those that strike during the day. A new study headed by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and at Yale ...

Researchers have discovered that mimicking cold exposure or fasting can trigger an immune response in the body that slows ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Two proteins ensure that cells can take up iron when needed. If both control proteins are switched off in mice, the animals develop severe anemia, as expected. Surprisingly, at the same time a cell ...

A more-developed version of the assay used in this study may help manage patients with acute decompensation of liver cirrhosis or acute-on-chronic liver failure before liver transplantation. Patients ...

The human body hates not getting enough oxygen. Without it, confusion takes over, breathing and heart rate change, and skin turns blue. It turns out that the immune system feels the effects of not ...