Ishiguro et al. describe CloneSelect, a multi-kingdom genetic barcoding system that uses barcode-specific CRISPR base editing to activate a reporter gene, enabling precise isolation of individual ...
Generative AI is moving full speed ahead in the biomedical space.
Our ranking is out, and it has a few surprises. In pole position — predictably — is Wegovy, the weight-slashing GLP-1 agonist, with AI-hallucinated proteins a close second. These are followed by ...
Micrograph of the mouse hindbrain with total protein content in cyan, lipids in magenta and presynaptic vesicles in yellow. Klimas et al. developed an expansion microscopy technique that retains ...
Publisher Correction: Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR–Cas9 ribonucleoprotein Kai Chen Hesong Han Jennifer A. Doudna Publisher CorrectionOpen Access18 Jun 2026 ...
Artist’s impression of a protein translocating through a nanopore. Yu et al. identify conditions that allow complete proteins to translocate through a nanopore when driven by an electroosmotic effect.
A scanning electron micrograph of phlegm in the trachea with bacteria shown in mauve. Charalampous et al. devise a metagenomics diagnostic method for bacterial lower respiratory tract infection that ...
Zhenan Bao and colleagues design and fabricate multilayered electronics that adapt to growing nerves, allowing chronic electrical stimulation during the fastest growth period in rats. The approach ...
Wearable sensors are evolving to provide accurate, continuous and wireless monitoring of our health and disease states. Using designs and materials that interface seamlessly with skin, accessing a ...
Single-cell proteomics maps protein dynamics in the developing human brain.
Hand-painted picture of a rice plant, showing the extensive root system. Zhang et al. show that rice recruits specific bacteria to the root microbiota to optimize nitrogen acquisition from soil. See ...
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