Please provide your email address to receive an email when new articles are posted on . In a cohort of Chinese patients with normal kidney function at baseline, NSAIDs had varying impacts on eGFR ...

Researchers from Kanazawa University find that propionic acid-class NSAIDs are conjugated with CoA by hepatic ACSL1, leading to liver toxicity via covalent binding with hepatic proteins Kanazawa, ...

Move over aspirin, a new formulation of ibuprofen might prove to be a "wonder drug." Scientists used mice and rats to show that ibuprofen arginate may allow people to take higher doses without the ...

Interindividual Response Variability, Laboratory Variability or Aspirin 'Resistance'? Individual drug response is a multifactorial, highly variable trait, being the final phenotypic result of ...

Houston, TX, March 23, 2010 - PLx Pharma, a pharmaceutical company developing gastrointestinal (GI) safer formulations of proven non-steroidal anti-inflammatory drugs (NSAIDs), announced today the ...

Combination analgesic products have been the mainstay of the treatment of moderate to severe dental pain for many years. Formulations containing an opioid analgesic, such as oxycodone, and a nonopioid ...

BUFFALO, N.Y. -- Stroke patients who use ibuprofen for arthritis pain or other conditions while taking aspirin to reduce the risk of a second stroke undermine aspirin’s ability to act as an ...

Selective cyclo-oxygenase (COX)-2 inhibitors were developed with the hope of producing lesser gastrointestinal (GI) side effects as compared with the conventional nonsteroidal anti-inflammatory drugs ...

Recent advances in dental therapeutics, pharmacology and toxicology have fundamentally reshaped clinical practice in dentistry. Enhanced understanding of drug mechanisms—from the actions of ...