LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a ...

Excess fat in brain immune cells weakens defenses against Alzheimer’s. Blocking fat storage restored their ability to fight disease. For many years, scientists believed that fat in the brain had ...

For decades, scientists believed Alzheimer’s was driven mainly by sticky protein plaques and tangles in the brain. Now Purdue ...

St. Jude scientists have uncovered the previously unknown lipid-regulated mechanism that initiates LC3-associated ...

Membrane proteins spend their time surrounded by lipids. For a long time, researchers thought those lipids didn’t really matter, that they were just a backdrop for the real players, an annoyance to be ...

MiR-93 promotes fatty liver disease, but vitamin B3 can counteract its effects. This discovery suggests a new treatment approach. Roughly 30% of people worldwide are affected by metabolic-associated ...

New understandings of how lipids function within tears could lead to better drugs for treating dry eye disease. A new approach has given Hokkaido University researchers insight into the synthesis and ...

New understandings of how lipids function within tears could lead to better drugs for treating dry eye disease. New understandings of how lipids function within tears could lead to better drugs for ...

A schematic illustration of the role of DHHC5 and CRYBG1 in controlling lacteal function and intestinal lipid absorption by maintaining the lipid raft association of VEGFR2. The proper functioning of ...

We evaluated whether LAP, developed as an index of cardiometabolic risk in a representative sample of the US population, [15] could be employed as a predictor of liver steatosis in the same Northern ...