The brain is the most energy-demanding organ in the body, in part due to its complexity. Its components are varied and intricate: comprising different cell types, including neurons designed to ...

Light microscopy is a cornerstone in life sciences technology, having experienced considerable diversification since its inception. This development becomes visible when considering the distinctive ...

Modern imaging is contributing significantly to giving us a better understanding of how our brains work. In the long term, this will also help us to treat learning disorders in a more targeted way and ...

Selective plane illumination microscopy (SPIM) is a type of light sheet fluorescence microscopy (LSFM), which is one such 3D imaging technique employing a thin sheet of light to illuminate cleared ...

Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to enable improved optical sectioning over a larger area of view. The advance makes the technique more ...

A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...

Are you studying complex biological structures such as vasculatures or neuronal networks but feel like you're not seeing the whole picture? Step into a new dimension with the UltraMicroscope Blaze™ ...

Key to understanding something like epilepsy is to be able to record highly transient events in biological tissues. Generally this is done using light sheet microscopy, which provides effectively a 2D ...

In the 1990s, researchers developed the first monoclonal antibody (mAb), trastuzumab (Herceptin), which works by blocking a receptor that is overexpressed in cancer cells. 1 This development was ...