Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at ...

The immune system helps fight off disease and allows our bodies to maintain a state of healthy function, known as homeostasis. In this regard, the immune system is made of two distinct responses that ...

T cells, together with B cells, are the workhorses of the adaptive immune response. And although some cells that are associated with the innate immune response can take on adaptive properties, it has ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at ...

Researchers have developed a novel non-steroidal anti-inflammatory from the active ingredient in a medicinal plant used throughout Southeast Asia. The novel compound doesn’t suppress the innate immune ...

Basophils trigger a cytokine cascade that improves antitumor immunity in mice, offering potential targets for cancer immunotherapy. “The results remind us: Don’t forget the basophil,” said study ...

It’s winter, at least in the northern hemisphere. That means cold and flu season is in full swing, and COVID-19 is still making a stand. Your immune system is your major line of defense, protecting ...

During severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, activated macrophages, dendritic cells, neutrophils, and natural killer cells are the first defense against infection.