When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

Pioneering research led by Brazilians describes the immune system's reactions in detail in the first living patient to receive a genetically modified pig kidney transplant.

The immune system can work in two ways: the innate immune system reacts to any foreign invaders that are identified by immune cells that look for such pathogens; but the acquired or adaptive immune ...

Innate immunity constitutes the body’s first line of defence against invading pathogens. This ancient, evolutionarily conserved system is activated within minutes of encountering foreign agents, ...

Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the GI tract. The two major types of IBD are Crohn's disease (CD) and ulcerative colitis (UC). Whereas in UC inflammation ...

Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the human body to better protect itself against potential ...

Cancer immunotherapies, including cancer vaccines, harness and amplify the immune system’s natural ability to detect and attack cancer cells. In this illustration, immune T cells (pink) attach to a ...

More than two-thirds of deaths from ovarian cancer are attributable to high-grade serous carcinoma. In one particularly ...

Across the world, only a few dozen people appear to carry a genetic glitch that lets them brush off viruses that flatten ...