Most cancer treatments—from chemotherapies to engineered immune cells—have a host of side effects, in large part because they affect healthy cells in the body at the same time as targeting tumor cells ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, ...

Researchers have developed a new class of antibodies that amplify the immune system’s ability to fight cancer. By clustering immune receptors that normally receive weak signals from tumors, these four ...

IIT Kanpur researchers, led by Professor Arun K Shukla, used cryo-EM to uncover the molecular basis of the atypical immune ...

C-type lectin receptors (CLRs) are a family of pattern recognition receptors that sense diverse microbial and damage-associated molecular patterns. Many CLRs, like Mincle and Dectin-3, are upregulated ...

Plants deploy cell-surface and intracellular immune receptors to recognize pathogens. In a comparative analysis of 808 angiosperm genomes, we reveal that during plant adaptation to diverse special ...

Immune cells in the uterus shortly after mating. Panels A–F show CD45+ immune cells, and panels G–L show ELANE+ neutrophils at two time points: 0.5 days (D0.5) and 3.5 days (D3.5) after mating. (A, G) ...

Study reveals how our immune system transforms across a lifetime—unlocking the potential for predicting disease risk and optimizing health before symptoms appear. Resource: Integrating single-cell RNA ...

Traumatic brain injuries (TBI)—even mild concussions—may trigger a chain reaction in the brain that disrupts neuronal ...