A consistent recent finding has been the strong association between hyponatremia and fractures. Initially, two case control studies reported the association of mild asymptomatic hyponatremia with bone ...

Richard H. Sterns, MD Hyponatremia may be the most common electrolyte disturbance seen in hospitalized patients. It is the most likely to lead to permanent or lethal complications if treated ...

Regulation of AVP secretion is extremely sensitive. Under normal conditions, large variations in the rate of AVP release can be effected by plasma osmolality changes as minuscule as 1–2%. 4 In ...

Sodium correction limits have been around since bed rest for back pain. The latter is gone but the former persists. While bed rest simply delays recovery, rapid sodium correction may cause osmotic ...

An observational study of nearly one million patients who underwent surgery suggests that preoperative hyponatremia (an electrolyte disorder in which sodium levels in the blood are low) was associated ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

In older adults, low sodium often results from certain medications, kidney issues, or infections. Because multiple factors may contribute, treatment depends on identifying the underlying cause. Sodium ...

Although exercise-associated hyponatremia has been reported in several studies, the effect of participation in long-distance triathlon races on plasma sodium levels is unknown. Prior studies have ...