Figure 1: Cervimycin structures and results of knocking out CerJ. A BLAST search for sequence-similar proteins with CerJ yielded sequences of proteins that have not yet been biochemically ...
A phase Ib trial of ERK inhibition with ulixertinib combined with palbociclib in patients (Pts) with advanced solid tumors. This is an ASCO Meeting Abstract from the 2021 ASCO Annual Meeting I. This ...
Risk of Cardiovascular Ischemic Events After Surgical Castration and Gonadotropin-Releasing Hormone Agonist Therapy for Prostate Cancer: A Nationwide Cohort Study We performed Cox regression to ...
Researchers at University of Michigan (U-M) Medical School and Wayne State University School of Medicine have identified, in fruit flies, a protein that, when missing, makes exercising in the cold ...
Scientists have revealed how Fanzor2's divergence from bacterial ancestors may make it a useful tool for future genomic engineering endeavors. A revolution in biomedicine is currently underway, driven ...
Most higher-order processing by the human and mammalian brain is thought to occur in the neocortex, a structure on the surface of the brain. Now researchers have found cells similar to those of the ...
N⁶-Methyladenosine is a ubiquitous modification identified in the mRNA of numerous eukaryotes, where it is present within both coding and noncoding regions. However, this base modification does not ...
The Plant Cell, Vol. 15, No. 12 (Dec., 2003), pp. 2856-2865 (10 pages) The flowering time of plants is tightly regulated by both promotive and repressive factors. Molecular genetic studies using ...
FDA-Approved Targeted Therapy: Dabrafenib plus trametinib (Novartis): This BRAF + MEK combination therapy was granted full approval by the FDA in 2017 and is the only approved treatment for patients ...
Structurally-guided discovery using high-resolution cryo-EM has delivered potent, DCAF16-dependent Targeted Glues™ of SMARCA2, with exquisite ...
Scientists at St. Jude Children's Research Hospital have revealed how Fanzor2's divergence from bacterial ancestors may make it a useful tool for future genomic engineering endeavors. A revolution in ...
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