The serine 31 (Ser31) phosphorylation modification (H3.3S31ph) in the N-terminal tail of the histone variant H3.3 can ...

A novel compound that inhibits the BAF chromatin remodeling complex causes regression in an animal model of the incurable cancer uveal melanoma.

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain fatty ...

Lung fibrosis is a debilitating disease affecting nearly 250,000 people in the U.S. alone with 50,000 new cases reported each year. There is currently no cure and limited available treatment options, ...