When mammalian cells die, they do not simply dissolve away. Instead, they are actively deconstructed and destroyed in defined and organized ways by various regulated cell-death mechanisms. One of ...

The role of Fibroblast Growth Factor 8 (FGF8) in embryonic development and organ formation is gaining increased recognition as scientists uncover its wide-ranging influence. FGF8, a powerful signaling ...

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical ...

Researchers from the A*STAR Institute of Molecular and Cell Biology (IMCB) have identified Nr1h2, a critical transcription factor essential for early embryo development. Published in Nature ...

In addition to endodermal and mesodermal cells, alcohol causes changes in DNA methylation in ectodermal cells (in blue), from which the nervous system and brain develop. During the tightly regulated ...

Scientists at EPFL have created a scalable 3D organoid model that captures key features of early limb development, revealing ...

Scientists have discovered a method of helping human stem cells thrive in an animal embryo—a key development in efforts to ...

Scientists found that embryonic skin cells “whisper” through faint mechanical tugs, using the same force-sensing proteins that make our ears ultrasensitive. By syncing these micro-movements, the cells ...

Scientists have used human skin cells to create fertilizable eggs capable of producing early embryos, an advance that could expand possibilities for fertility treatment, according to new research. The ...

Researchers have identified Nr1h2, a critical transcription factor essential for early embryo development. Their findings enhance our understanding of gene regulation during blastoid formation and ...