T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged campaign against a chronic condition—like a viral infection or cancer—the body ...

Scientists have discovered how two transcription factors form a reciprocal regulatory circuit that controls T-cell exhaustion and migration during viral infection, which may inform future therapeutic ...

There exists a complex synergistic relationship among cancer, circadian rhythms, and aging: aging is a major risk factor for cancer, disruption of circadian rhythms promotes tumor initiation and ...

However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...