The goal of gene therapy for patients with hemophilia A is to safely impart long-term stable factor VIII expression that predictably ameliorates bleeding with the use of the lowest possible vector ...

This is a preview. Log in through your library . Abstract Understanding how the expression of transcription factor (TF) genes is modulated is essential for reconstructing gene regulatory networks.

Spinal motor neurons are specified to innervate different muscle targets through combinatorial programs of transcription factor expression. Whether transcriptional programs also establish finer ...