In eukaryotes, the tight or loose packaging of the genes in chromatin (DNA plus specific proteins) can control whether the genes can be expressed to form their encoded product. Chromatin is usually ...
Transcription by Pol II is dependent on a number of multi-subunit complexes including TFIID, a general transcription factor complex, and SAGA. Both deliver the TATA-box binding protein (TBP) to ...
Highly repetitive regions of junk DNA may be the key to a newly discovered mechanism for gene regulation. The discovery during the Human Genome Project in the early 2000s that we humans have only ...
Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is ...
Intrinsically disordered regions in transcription factors enhance both target binding probability and search efficiency.
“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...
An ambitious and revolutionary initiative aims to map every cell of all eukaryotic life on Earth. The result will be a ...
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