Compact CRISPR alternative uses bacterial proteins to insert large DNA segments

A new engineered gene-editing system, proven in bacteria and showing promise for use in plants, animals and humans, addresses ...
BIOENGINEER

Antibody-DNA Hybrids Push Ultrasensitive Diagnostics and RNA Drugs Forward

Few molecular designs manage to bridge two worlds as different as immunology and nucleic acid chemistry, yet ...
BIOENGINEER

Hidden RNA switches reshape cancer proteins and sabotage drug targets

A comprehensive multi-omics study catalogues thousands of cancer-specific isoform switches in melanoma, ovarian cancer, and ...
Nature

Translation: DNA to mRNA to Protein

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Mapping the 'social network' of proteins in the cell to understand how genes shape living things

One of biology's fundamental questions is how our genes shape who we are. Adrian Serohijos and Stephen Michnick, professors ...
Nanowerk

Gene Expression: Definition, How It Works, Regulation, and Uses

Definition: Gene expression is the process by which a cell turns the information in a gene into a functional product, such as an RNA molecule or a protein. In simple terms: gene expression is how a ...
Medical Xpress

RNA is key to the dark matter of the genome. Scientists are sequencing it to illuminate human health and disease

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...