Geleophysic dysplasia (GD) is a rare and progressive genetic condition characterized by short stature, brachydactyly, joint limitations, and a unique facial appearance as well as cardiac and ...

Konstanz researchers identify an enzyme that plays a role in the migration of cells in our body—not only during normal tissue formation and wound healing, but also when tumor cells metastasize. This ...

The epithelial microenvironment is incredibly dynamic, subjected to mechanical cues including cyclic stretch. While cyclic cell stretching platforms have revealed epithelial cell reorientation and gap ...

A new study integrated mathematical modeling with advanced imaging to discover that the physical shape of the fruit fly egg chamber, combined with chemical signals, significantly influences how cells ...

Cell migration is a multistep process essential to various physiological functions, including immune cell movement and embryonic development, as well as pathological conditions like tumor metastasis.

Traditional electrotaxis assays place electrodes directly into the cell culture medium, which inevitably drives current through the sample. That current can alter pH, create chemical gradients, and ...

As an embryo grows, there is a continuous stream of communication between cells to form tissues and organs. Cells need to read numerous cues from their environment, and these may be chemical or ...

How do cells move from A to B through our body to build functional tissues? And how is this process regulated? The answers to these questions are essential – for example, for our understanding of how ...

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear. Research published in the Biophysical Journal shows that ...

Jian Zhang, an assistant professor of biomedical engineering, will study how mechanical forces and cellular energy constraints guide cell motion in engineered tissue models.

Migrating newborn neurons suffer routine double-strand DNA breaks from physical stress during brain development.