Blocking Caspase-2 (the liver’s guardian enzyme) to treat fatty liver may produce chronic damage and multiply the risk of ...
New research has shown that inhibiting caspase-2 to treat fatty liver disease may increase inflammation, fibrosis and cancer ...
Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead increase the risk of chronic liver damage and cancer as we age.
Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead ...
Ventus Therapeutics, a clinical-stage biopharmaceutical company advancing multiple small-molecule programs for autoimmune, ...
Most unnecessary or dangerous cells such as virus-infected cells commit suicide by activating an in-built suicide program. This type of cell death is referred to as "programmed cell death". Until ...
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that ...